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Schematic illustrating different nuclear TAF2 compartments. Half circles in TFIID represent histone-fold domain partners and the lines represent protein domains not resolved by cryo-EM. In (A), (E), and (H), GFP and control pull-downs were performed as technical triplicates. Dashed red lines indicate the threshold between non-significant and significant interactors. In (A), (E), and (C), a two-samplettest with FDR = 1% andS0= 1 was performed; in (H) the FDR was set to 0.1% andS0to 1. In (D) and (H), data are representative ofn= 2 biological replicates.
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