Genome-wide copy number alteration profiles of gain and loss for HER2E (purple), LumA (blue), and LumB (light blue) tumors. Statistical tests: Mann-Whitney U test (A-D, F, I); Fisher’s exact test (G-H); Fisher’s exact test + FDR correction (K). Significance annotation: * ≤0.05; ** ≤0.01; *** ≤0.001; **** ≤0.0001. All reported p-values from statistical tests are two-sided. Boxplot elements correspond to: (i) center line = median, (ii) box limits = upper and lower quartiles, (iii) whiskers = 1.5x interquartile range. Top-axis in boxplots reports group sizes. Source data are provided as a Source Data file.