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Quantification of Dnmt3a+/+ and Dnmt3a-/- embryo body weight at E16.5. Data are normalized to Dnmt3a+/+ controls and per litter. n ≥ 7. Shown are mean ± SD. The statistical significance was assessed by Mann-Whitney test (A, B, D, G, and H).*p< 0.01,***p< 0.001.

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