Density Plot from Scientific Research

Distributions of the number of cell identity changes required per colony to capture the observed tip states. The number of cell identity changes assuming a unidirectional ‘HSC-first’ model (HSCs give rise to MPPs) is shown in blue. The required cell identity changes for the opposite ‘MPP-first’ model, in which MPPs give rise to HSCs, is shown in red. The null distribution, in which tip states are randomly reshuffled, is shown in grey.

DOI