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Heatmap comparing 5PSeq coverage at log2ratio of -17 nt (F1) and -18 nt (F0) relative to the A-site of codons in YPD and CSM. The codons are ordered by the differences of frameshift index between YPD and CSM (i.e., log2(F1/F0)YPD- log2(F1/F0)CSM). Codon stability coefficients (CSCs) and codon optimality from Presnyak et al.10
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