Pie Chart from Scientific Research

Identification of Ga12/13-coupled GPCRs expressed by T cells. Left, expression in naive and activated T cells of genes encoding Ga12/13-coupled GPCRs with moderate to high coupling index to Ga12 or Ga13 (log relative intrinsic activity > –1) identified in ref. 30 . Right, known ligands or agonists of expressed receptors. 9-HODE, 9-hydroxyoctadecadienoic acid; LPA, lysophosphatidic acid; LysoPI, lysophosphatidylinositol; LysoPS, lysophosphatidylserine; PGE 2 , prostaglandin E 2 .

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