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Open access visualization of Illustration, CDC73 Domain Organization, N-Terminal Domain, Multiple Sequence Alignment, CDC73-KIM
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DOI: 10.1016/j.molcel.2025.04.012

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(Top) Schematic of CDC73 domain organization. NTD, N-terminal domain. (Bottom) Multiple sequence alignment of CDC73-KIM in humans (Homo sapiens), zebrafish (Danio rerio), fruit fly (Drosophila melanogaster), and the worm (Caenorhabditis elegans). Fully conserved residues among the listed sequences are shaded in red. KIM regions important for T-loop opening and the cyclin K interaction indicated.

#Illustration#CDC73 Domain Organization#N-Terminal Domain#Multiple Sequence Alignment#CDC73-KIM#Conserved Residues#T-Loop#Cyclin K

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