Quantification of in vitro osteogenic assays with small molecule treatments on hSSCs from seven patients. Insert shows quantification of combined patient hSSCs relative to combinatorial DMH1 + SAG treatment. Data shown as mean + standard deviation of the mean (SEM). Two-tailed Student’s t test versus combinatorial treatment with Welch’s correction or Mann-Whitney test to correct for unequal variances or non-normality. n = 14 from independent duplicates of seven patient hSSCs.