WT HeLa Kyoto cells and HeLa Kyoto cells treated with TSA before mitotic entry. Exemplary maximum-intensity projected micrograph of metaphase chromatin (DAPI, gray) with full chr2 traces (DNA-FISH, multi-colored). Data representative of 212 WT metaphase cells from 3 independent experiments and 205 prometaphase/metaphase TSA-treated cells from 2 independent experiments.
