Protein Structure from Scientific Research

Cryo-EM map of TAS1R2-TM with the bound G protein complex. Green, TAS1R2-TM domain; orange, miniGs/gust; pink, Nb35; blue, GNB1; purple, GNG2. Note that this map was reconstructed from the class 3 particle population (Figures S2andS8), distinct from the set used to generate the full-length receptor map shown inFigure 1. The G protein complex model was built based on the consensus map shown in (A). SeeFigures S8C–S8F for a description of the unique TM arrangement in this particle class.

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