Microscopy from Scientific Research

Open access visualization of Microscopy, Line Plot, TDP-43 Aggregation, Nucleocytoplasmic Transport, iPS-MNs
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DOI: 10.1016/j.cell.2025.04.039

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TDP-43 aggregation impairing nucleocytoplasmic transport in iPS-MNs. Neurons expressing TDP-43ΔNLSalone or together with TDP-43-Myc with intact NLS were stressed with 100 μM arsenite for 90 min, and images were acquired for importin-α or TDP-43-Myc staining. Scale bar, 2 μm.

#Microscopy#Line Plot#TDP-43 Aggregation#Nucleocytoplasmic Transport#iPS-MNs#TDP-43ΔNLS#TDP-43-Myc#Arsenite#Importin-α Staining#Scale Bar

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