ABE ENVLPE for the disruption of a splice donor (SD) site of the first intron in the B2M gene was transduced into the indicated cell lines. Editing was quantified in HEK293T via NGS (F) or Sanger sequencing (G) 72 h after transduction. Points in (F) and bars in (G) represent n= 3 biological replicates. Log2(VrelSN): relative transduction volumes in 2x dilution steps.
