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MWAS analysis upon adding a covariate of the lead variant in the known adaptative loci. The y -axis denotes LTA DMSs that are annotated to the known adaptive loci, such as EGLN1 , EPAS1 , and HLA-DQB1 , and the x -axis represents the effect size for MWAS analysis with error bars representing standard errors. Colors indicate two different models before/after adding the lead variant as a covariate.
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