Manhattan Plot from Scientific Research

Manhattan plots of MWAS results for STA ( a ). The x -axis denotes the genomic position, and the y -axis denotes the MWAS association -log10 (bacon-adjusted P value) times the sign of the effect size (the difference in the mean DNAm level of the target group from the control group). The dashed lines indicate the methylome-wide significance thresholds (bacon-adjusted P value = 1.12x10-7 ). DMSs were annotated to the nearest genes.

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