Cumulative histopathological scoring shows a brief increase for the QDPMMA MNP group that decreases over time (dotted line shows the maximum total score of 18). (Untreated skin, 3 days and 30 days had n = 3 biological replicates; 70 days had n = 4 biological replicates; six tissue samples per biological replicate. One-way analysis of variance (ANOVA); confidence interval, 95%).