AlphaFold2 model of the REC region of OrufIscB-REC with swapped loops from AlphaFold2 models of other REC domains labeled in three shades of red corresponding to regions 1, 2 and 3. The AlphaFold2 model of the swap 49 loop is shown for region 1. Conserved amino acids flanking each swap region are depicted as side chains. Sequence alignment entropy is mapped onto the structure as a white-to-blue gradient, with entropies of up to 3 being shown as blue. ZF, zinc finger. Each asterisk denotes a swap site.
