Strip plots illustrate two-way interactions between region (bilateral putamen and caudate) and visit (baseline, before transplant and after transplant), adjusting for mean-centered age and disease duration at baseline. Bootstrapped means and 95% confidence intervals (bias-corrected and accelerated procedure, 10,000 replicates) by surgical device (TRN3/TRN4/R–L/control) and visit (before transplant/baseline and after transplant/18-month follow-up for transplant/control, respectively) were generated considering data from all putamen unilaterally and plotted for both [ 11 C]PE2I BP ND ( f ; device n = 4 (TRN3), 6 (TRN4), 6 (R–L) and 32 (control)). Partially transparent lines represent data from individuals, whereas opaque lines and error bars represent estimated marginal means and 95% confidence intervals, respectively. Significance was analyzed by Tukey-adjusted post hoc tests; * P < 0.05; ** P < 0.01; *** P < 0.001 (two sided); Ct, control; MA, most affected side; LA, least affected side.