Protein Structure from Scientific Research

Open access visualization of Protein Structure, Cytoplasmic Facing, Wild-type Protein, Luminal Facing, E33A Variant
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DOI: 10.1038/s41586-025-09069-w

DOI

Comparison of the cytoplasmic-facing wild-type protein (bundles in orange and teal) and luminal-facing E33A variant (pink). Left, view from the cytosolic side with TM4b, TM6, TM8 and TM9 moving particularly inwards for gate closure. Right, view from the ER luminal side with TM1, TM3, TM4a and TM9 moving particularly outwards for gate opening.

#Protein Structure#Cytoplasmic Facing#Wild-type Protein#Luminal Facing#E33A Variant#ER Luminal Side#Gate Opening#Gate Closure

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