Protein Structure from Scientific Research

Cartoon representation of SLC35B1 harbouring the expected DMT-fold. The overlapping V-type helices TM1TM2 and TM8TM9 make up one bundle (light orange) and TM3TM4 and TM6TM7 make up the other (teal). TM5 and TM10 (grey) are positioned peripheral to the V-type helices, which in some DMT-fold members mediate homodimerization with TM5 and TM10 of the neighbouring protomer. Access to the ER lumen is closed (obstructing helices boxed) but open to the cytoplasm.

DOI