Scatter plot depicting the presence of six mitochondrial variants in the different clones identified using EPI-Clone from X.2. Cells were scored as positive for the variant if at least 5% of reads supported the variant. The enrichment of variants in the identified clones was determined by a two-sided binomial test. The identified clones were classified as B cell, T cell or NK cell clones if at least 80% of cells were from a single lineage or as multilineage clones otherwise.