Bar Plot from Scientific Research

Cal-27 cells were pretreated with an IL-1 receptor antagonist (IL-1RA) and neutralizing antibodies against IL-1alpha (nIL-1alpha) and IL-1beta (nIL-1beta), exposed to 0 (Sham), 2, 4, and 8 Gy, then IL-6 measured in cell culture media by ELISA. Average values were normalized to Sham control and plotted as fold change. Bars represent the mean of n = 3 independent experiments. Error bars represent standard error from the mean. * p < .05; ** p < .01; *** p < .001; **** p < .0001. ND: non-detectable

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