Bar Plot from Scientific Research

Prolonged incubation, especially with the higher Ciprofloxacin concentration (75 M, 3 days) resulted in elevated mitochondrial NADPH levels in PDL-hTERT cells, potentially as a result of the inhibition of the reverse reductive carboxylation reaction of IDH2 that is reported to be prominent in settings of mitochondrial dysfunction (average and mean of 3 independent experiments plotted).102In the bar plots inB,CandDthe statistical relevance based on one-way ANOVA with Dunnett's multiple comparison test is depicted (ns meaning P-value >0.05, * P-value0.05, ** P-value0.01, *** P-value0.001, **** P-value0.0001).

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