x-axis, genomic position; y-axis, -log 10 (P -value) of association (two-sided Z -test, unadjusted for multiple tests); red and green points, regions previously and newly associated, respectively, with psoriasis susceptibility at genome-wide significance (P = 5 x 10 -8 ) in European ancestry populations; solid horizontal line, genome-wide significance threshold; dotted horizontal line, y-axis break at 10 -30 ; chromosomes (labelled 1-22) are alternately shaded for clarity.
