Representative diagram of all derived signatures from mice and humans. Each dot represents a signature and is sized by its number of genes. The dot color is the respective enrichment for each signature compared to previously known senescence markers (-log 10 Hypergeometric P -value). Each signature is connected to its most similar signature and the color of the connection is based on the cosine similarity. Signatures without significant overlap are connected with gray lines (Hypergeometric FDR P -value).
