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There is an insignificant overlap between a universal organismal aging signature and previously reported senescence markers (p = 0.58, Hypergeometric). The universal signature is comprised of genes present in at least 50% of the cell-specific gene sets elucidated by differential expression between young and old cells previously. Created in BioRender. Rehman, J. (2025) https://BioRender.com/w72f903

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