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Not shown in this figure are dimensions for sex, CD4 count, NNRTI resistance acquisition, NRTI resistance acquisition, and mortality (appendix pp 311). 140X=drug-resistance mutations at integrase position 140 (ie, Gly140Ala, Gly140Cys, and Gly140Ser). 148X=drug-resistance mutations at integrase position 148 (ie, Gln148His, Gln148Lys, Gln148Asn, and Gln148Arg). MARISA=Modelling Antiretroviral Drug Resistance in South Africa. NNRTI=non-nucleoside reverse transcriptase inhibitor. NRTI=nucleoside reverse transcriptase inhibitor.

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