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MCF7 cells transfected with siCTL, siPRMT1-1, or siPRMT1-2 were then cultured in normoxia (20% O2) or hypoxia (1% O2) for 6 h, followed by immunoblotting (IB) analysis to examine the expression of selected genes as indicated. The mRNA expression value and significance test are included inTable S3(mean SEM,*p< 0.05,**p< 0.01,***p< 0.001).
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