Protein Structure from Scientific Research

Comparison between GLUT9 and GLUT1. The inward-open human GLUT1 bound ton-nonyl--D-glucopyranoside (-NG) (PDB:4PYP, gray) is superimposed with human GLUT9 bound to urate (colored) (left). Zoomed-in views (center and right) show differences in the substrate binding sites. GLUT1 residues are labeled, with the corresponding residues in GLUT9 in parentheses. Hydrogen bonds are indicated by dotted lines.

DOI