Induction of LTP by 400 Hz, patterned burst stimulation of medial perforant path input to DG cells in vivo. Top panel: illustration of the electrode placement for unilateral induction of LTP. Bottom panel: time course plots of fEPSP slope values recorded before and after HFS (indicated by arrows). Values are mean ± SEM in percent of baseline. Rats were killed at 1 and 3 h post-HFS (stippled line). Inset shows representative field potentials obtained at the end of baseline recording and the last 5 min of post-HFS recording.
