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Clustering coefficient (CC) for the characterization of connectivity in the CaMKII-GluN2B condensates (seeSTAR Methods). In the condensate, CaMKII proteins (green) were bound to other CaMKII proteins via GluN2B (purple). If a target CaMKII protein (highlighted) binds to six neighboring CaMKII (N= 6) that have six surrounding connections (nedge=6, left case), this givesCC =2nedge/N(N1)=0.4. IfN= 6 andnedge=3, this givesCC =0.2 (center case), and ifN= 6 andnedge=0, this givesCC =0.0 (right case). In general, the largerCCdenotes a denser local connectivity.

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