Network from Scientific Research

The hub genes and gene-metabolite networks for lipids are shown. In the circle plot, the bar charts on the outer ring display the mGWAS signal density in 2-Mb genomic windows. In the network plot, the node sizes from largest to smallest indicate hub genes, genes, and metabolites. The edges between genes and metabolites indicate significant associations (-log10(p) > 7.3), and the edges between metabolites represent Pearson correlation coefficients r > 0.5. Different colors represent distinct metabolite categories (see legend). All hub genes are labeled in both the network and the circle plot.

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