MCF10DCIS control (Ctrl) or RRAGC KO #C3 cells were injected subcutaneously in nude mice. At weeks 1, 3, or 5 post-inoculation, tumors were dissected, and sections stained with indicated markers. Representative images of week 5 tissue sections of different tumor xenografts labeled for TFEB. N, nucleus; n, necrosis; s, stroma.