Workflow from Scientific Research

Schematic of workflow to infer cell migration parameters. Bias and persistence angles are calculated from cell-tracking data (1) and fed into biased-persistent random walk model (2) (STAR Methods). The bias parameter b sets the width of a normal distribution for the bias angle through sigma_b^2 = -2log(b), and similarly for the persistence parameter p, whereas the weight parameter w sets the balance between biased and persistent steps. A posterior probability distribution over the parameters b, p, w is calculated through Bayesian inference (3).

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