Upper: example of empirical and simulated slow-wave activity (SWA) across 48 h (24 h of baseline + 6-h sleep deprivation + 18-h recovery) in an example WT (left) and rlss (right) mouse. Lower: zoomed-in inserts (see x axis values) of a 4-h section from the corresponding upper panels. Colors indicate the corresponding vigilance state, also shown underneath each panel as a hypnogram.