Percentage of periods of neuronal silence (“OFF-periods”) longer than a given duration (x axis) for all individual channels of rlss (light blue curves, n(mice) = 5) and WT mice (dark blue curves, n(mice) = 5). BL conditions during the light and dark phases. Only NREMS is considered here. Each animal is coded with a different symbol (x, o, etc.), showing how all rlss mice have at least one channel in the upper right-hand corner of the graphs (prolonged OFF-periods), unlike any of the WT mice. See also Figures S1B–S1D, S2, and S3, and Video S1. n(WT) = 5 (4 beyond BL-L phase) with resp. 6, 10, 6, 7, and 6 channels in each mouse (total = 35 channels), n(rlss) = 5, with resp. 9, 6, 8, 5, and 7 channels in each mouse (total = 35 channels). BL, baseline; SD, sleep deprivation.
