Model of early infection. (i) Goslar injects its genome along with its vRNAP (pink) into the membrane-bound EPI vesicle. (ii) Supported by nucleotide import into the EPI vesicle (NTPs), early viral genes are transcribed by the vRNAP, and the mRNAs are exported to the cytoplasm for translation by host ribosomes (yellow). (iii) The viral genome is transferred from the EPI vesicle to the ChmA shell (dark blue). (iv) DNA replication begins. Scale bars: (A) and (B) 1 m; (D) 0.5 m.
