Heatmap of moderated t-statistics for 500 mM NaCl IP-MS screen. Proteins significantly enriched in at least one experiment (IP vs. complement, adj.p< 2e-4 and log2(fold-change) > 1, rows) in TF and untagged control IP-MS experiments (triplicate averages, columns). Proteins (except TFs without interactions) are clustered using hierarchical clustering (complete linkage) based on the correlation between their t-statistic vectors. Complex annotations: NuA4 and SAGA subunits in blue and purple, respectively. Columns are split into untagged control, no interactions in 500 mM NaCl IP-MS (TFs with no detected interactors at high salt), and interactions in 500 mM NaCl IP-MS (TFs with interactions at high salt).
