Lrat Cre;Esr1 fl/fl or control Esr1 fl/fl female littermates were fed with the NCD or MCD diet to induce liver fibrosis. mRNA levels of fibrosis-related genes in the liver tissues were examined by qPCR. Data are presented as mean ± SEM; * P < 0.05, n.s. not significant (two-way ANOVA test). n = 5 for control Esr1 fl/fl or Lrat Cre;Esr1 fl/fl mice under the NCD condition; n = 11 for control Esr1 fl/fl mice and n = 13 for Lrat Cre;Esr1 fl/fl mice under the MCD condition.