Microscopy from Scientific Research

Cytochalasin-D-treated monolayer stained for VE-cadherin after 7 h of pressure showing round cells (i). Evolution of the probability distribution of the cell orientation (ii) and the associated nematic order parameter Q (iii) before pressure increase (150 Pa, n = 8), and after 7 h of high pressure for the control (650 Pa, n = 7) and cytochalasin-D-treated (CytoD, n = 3) monolayers. Schematic showing round cells after actin depolymerization by cytochalasin D treatment, despite the circumferential stretching force (iv). Scale bar, 50 μm.

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