The effect of felzartamab treatment on gene expression (ΔΔlogFC) from week 24 to week 52. The circles represent the ΔΔlogFC (y-axis) and P values (x-axis) of individual genes compared between biopsies from placebo (n patients = 10) and felzartamab (n patients = 10) arms from week 24 to week 52. All biopsies represent biological replicates. Functional enrichment by differentially expressed genes is included in a – c. The gene labels represent the top ten genes by representation across all enrichment terms.
