Effects of ( f ) pre-crosslinking density and ( g ) microparticle size on the imbibition rate (within 10 seconds) and imbibition ratio (after saturation) of oHA microparticles. Data are presented as means s.d. ( n = 3 independent samples for f and g ). All statistical analyses were performed using an unpaired two-tailed Student t -test. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001 (for comparison of imbibition rate); # p < 0.05, ## p < 0.01, ### p < 0.001, #### p < 0.0001 (for comparison of imbibition ratio). Comparison was performed between pre-crosslinking densities of 0, 9.8%, or 16.5% versus 13.5%, as well as between particle size of 180–325 m, 120–180 m, or 38–75 m versus 75–120 m. Source data are provided as a Source Data file.
