In vitro 24-h Luciferase-based cytotoxicity assay comparing the four different CLL1CART against U937. Data are normalized to UTD T cells ( n = 3 technical replicates). Statistical analysis was performed by mixed-effects model with Geisser–Greenhouse correction and Tukey’s multiple comparisons test. p -values: CD8 4-1BB vs. IgG4 CD28 E:T 1:1 = 0.0042; CD8 4-1BB vs. CD28 E:T 1:1 = 0.0101; CD8 4-1BB vs. CD28 4-1BB E:T 2:1 = 0.0080; E:T 1:1 = 0.0012.
