Bubble Plot from Scientific Research

Scatter plots of the median L2FC for each gene in vitro and in vivo in CRISPR screens of, in order from the top left: VAND in CAST/EiJ mice, RH ∆HXGPRT in PWD/PhJ mice, PRU ∆HXGPRT and VEG in C57BL/6J mice. The colour and size of each point reflects the Discordance/Concordance (DISCO) score, and the dashed grey line indicates equal L2FC. Displayed data are thresholded for L2FC in vitro > -1 according to published in vitro whole genome screens 53 . Data points with a L2FC in vivo < -1.5 are labelled in addition to ROP18 as control.

DOI