Microscopy from Scientific Research

Cell proliferation analysis in different types of Caco-2 cell tumors by EdU staining. Various types of mScarlet-positive Caco-2 cell tumors, such as flat monolayers (middle, FM), ACF-like (top, ACF), protruded (top, PR) and invasive tumors (top, IV), exhibited a significant presence of EdU-positive tumor cells. By contrast, normal epithelial cells adjacent to tumors were deficient in cell proliferation (top and middle, white arrowheads). (bottom) Control mouse cecum with many proliferating normal epithelial cells.

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