pTyr residues were detected in HaCaT lysates post 500 nM BK or cBK stimulation for 15 min in the presence/absence of B 2 (HOE140) or B 1 (R715) receptor inhibitors. Blots were then probed for -actin as a load control. Representative result. Results are expressed as mean SEM. Statistical significance was calculated with One-way ANOVA with Dunnett and Sidak post hoc. *** if p < 0.001