BK and cBK were cleaved by ( D ) CPM, and reaction products were separated via HPLC ( n = 3, biological replicates). Results are shown as % of cleaved peptide ± SEM when compared to respective loading control – BK or cBK. Statistical significance was evaluated with paired t-test, * if p < 0.05, ** if p < 0.01; *** if p < 0.001