Bar Plot from Scientific Research

Prediction for the ectopic activation of Notch by combinations of Dl- and Mib1-variants in mib1 mutant discs. Note that the combination of Dl-NB2A with Mib1ΔREP is predicted not to function, since the interaction of both the NB with the MZM and the CB with the REP should be compromised. It should therefore cause a similar phenotype as the other combinations in the red frame. However, the combination of Mib1ΔREP with Dl-CB2A should lead to the reduction of ectopic activation in a similar manner like the combination of Dl with Mib1ΔREP (combinations in the blue frame.

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