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Blood analytes from treated mice. M, mock; L, Lipodox; H, HerDox; AST, aspartate transaminase; ALT, alanine transaminase; BUN, blood urea nitrogen; CRE, creatinine. Significances show comparison of HerDox versus Lipodox groups. * P = 0.0228 (AST), *** P = 0.0005 (ALT), ** P = 0.0099 (BUN), determined by unpaired t -tests at 95% CI ( n = 8 per cohort).

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