Bar Plot from Scientific Research

Dual luciferase reporter assay displaying BMP6 responsiveness towards constructs with differently spaced pGC-SBE homocomposite motifs. BMP6 responsiveness is observed, when at least two pGC-SBEs are separated by a 5-bp spacer. Data are shown as mean fold induction to unstimulated cells (gray line) in relative luciferase units (RLU) SD (c g n = 315). Statistical significance was calculated in between samples using one-way ANOVA and Tukeys post hoc test; * P < 0.05, ** P < 0.01, *** P < 0.001, and **** P < 0.0001

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