HER3 and caveolin-1 (CAV1) localization relative to vasculature (claudin-5) in brains of non-diseased 8-week-old female BALB/c mice, showing 1 µm serial planes (z3–z5) along the viewing z axis. Arrows, HER3-positive areas aligning with CAV1 and claudin-5-positive areas. Graph compares each biomarker at vessel versus non-vessel areas. Significances determined using two-way ANOVA (95% CI) and Sídák post hoc test ( n = 6). Data presented as mean ± s.d.
